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This is a new and very important discovery. New research is currently underway to understand these effects in more detail and better discern the role CBD could possibly play in the role of Parkinson’s management. If these findings are shown to be therapeutically relevant through future research, we can expect to see CBD become a primary treatment option for Parkinson’s disease.

What’s the Recommended Dose of CBD? There aren’t enough clinical studies to highlight a specific dosage range for Parkinson’s disease. However, there’s a lot of research on the use of CBD use for other neurodegenerative diseases, such as multiple sclerosis. Heavy doses of CBD are usually required to produce benefits for these conditions.

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To find your dose, use the CBD oil dosage calculator below. For Parkinson’s disease, you should aim to use the supplement long-term. Heavy Strength CBD Oil Dosage Calculator What is Parkinson’s Disease (PD)? Parkinson’s disease (PD) is a neurodegenerative disorder affecting the part of the brain responsible for manufacturing dopamine.

They begin with nonspecific issues like hyposmia (reduced sense of smell), sleep disorders, constipation, and obesity up to 20 years before the more characteristic muscular issues such as rigidity, tremors, and falling. As the disease progresses, non-motor symptoms such as hallucinations, delusions, dementia, and depression can appear and worsen over the next 20 years.

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A common finding in PD patients is an abundance of Lewy bodies — clusters of proteins inside the neurons that don’t break down as they should through normal enzyme reactions in the brain. As these Lewy bodies become more abundant and build up, they kill the neurons. This type of neuron injury is also characteristic of other neurodegenerative disorders including Alzheimer’s disease (AD).

In the case of Parkinson’s, the majority of these protein clusters are in the basal ganglia of the brainstem — specifically in the substantia nigra pars compacta neurons. What Are The Signs & Symptoms of Parkinson’s Disease? Dopamine & Parkinson’s Disease As the dopamine-producing neurons in the brainstem are lost, it becomes more difficult to manufacture the dopamine the brain needs to function properly.

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Without enough dopamine, symptoms like muscle tremors, lockjaw, weakness in the arms and legs, and poor balance are more frequent. Norepinephrine & Parkinson’s Disease Norepinephrine and epinephrine is structurally similar to dopamine and is built through the same pathway as dopamine. Therefore, epinephrine levels also suffer a decrease in production from Parkinson’s disease [1].

As they start to become less abundant in the brain and blood vessels, we lose the ability to regulate autonomic functions including heart rate and blood pressure. What Causes Parkinson’s Disease? The cause for Parkinson’s disease is still unknown — however, there are a few factors that we now know contribute to the condition over time.

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Newer studies, however, found at least two gene variants related to Parkinson’s disease [5] — LRRK2 and GBA genes, albeit rarely. Most cases by far are idiopathic. (pesticide) The 5 Stages of Parkinson’s Disease Stage 1 Symptoms appear but are mild in nature. They usually don’t interfere with daily activities.

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Stage 2 Stage two involves an increase in the severity of symptoms discovered in stage one and the development of symptoms affecting movement. It may be more difficult to walk normally, maintain correct posture, and normal tasks begin to become difficult. Usually, people in stage two don’t require outside assistance.

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People in stage three may need assistance, while others remain independent. Stage 4 By stage four, symptoms have become pronounced. Standing is possible, but walking requires the support of a walker or another person. Daily activities such as eating, bathing, and moving around require assistance. People at this stage are not able to live independently.

Patients are unable to stand or walk on their own and are usually confined to a bed or wheelchair. Hallucinations and delusions may appear during this stage. Full-time assistance is required for people in this stage of disease. How is Parkinson’s Disease Treated? Most of the treatments for Parkinson’s disease are aimed at managing symptoms in order to optimize a patient’s quality of life.

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The medications will also need to be readjusted over time, along with regular follow ups with a neurologist. (SNRIs, SSRIs, TCAs)(MAO-B Inhibitors, amphetamines) Key Takeaways: Can CBD Help With Parkinson’s Disease? There’s no cure for Parkinson’s disease — most of the treatment options available, including CBD are used to slow the progression of the disease and manage symptoms to improve a patient’s quality of life.