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Published Aug 20, 21
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Many of these receptors are in areas of the brain impacted by Parkinson’s disease (the basal ganglia). The main cannabinoid is tetrahydrocannabinol (THC). This can cause the feeling of being “high”—described as happiness, amusement or contentment — that is commonly associated with marijuana. THC may help nausea, pain or muscle spasms, but it also can have negative effects on mood, behavior and thinking.

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Food and Drug Administration (FDA)-approved prescription cannabis medications also are available for specific conditions, such as epilepsy or cancer- or AIDS-related symptoms. The amount of THC, CBD, other cannabinoids and other (sometimes unknown) substances varies across products. Sometimes, the levels of these contents may not be known. And even if the product does have a label, studies have shown the label may not fully or accurately represent what’s inside.

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Most states have their own regulations, but these vary. Mobile Hydraulic hose repair near me Newcastle.) Still, it’s important to read labels, ask questions, and have a general idea of the amount of THC or CBD in the product. For those who choose to try cannabis, use caution — start with a low dose and increase slowly (if at all).

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(See below.) There are many anecdotal reports of benefit. But controlled trials — on motor and non-motor symptoms as well as dyskinesia (involuntary, uncontrolled movement) — have not yet proven the safety or benefits of cannabis in Parkinson’s. Clinical trials have generally had mixed or conflicting results (some positive, some negative).

But many also report side effects. This leaves patients, doctors and researchers with insufficient evidence to guide use. In low doses, cannabinoids appear to be relatively well tolerated. But, like all treatments, they have potential side effects: new or worsened nausea; dizziness; weakness; hallucinations (seeing things that aren’t there); mood, behavior or memory/thinking (cognitive) changes; or imbalance.

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The potential risks on cognition, mood and motivation (to exercise or participate in other activities, for example) are especially important for people with PD. Cannabis also could interact with other medications you are taking. Emergency On-site Hydraulic hose near me Newcastle. While interactions are largely unknown, adding cannabis to a complex regimen of Parkinson’s and other prescription medications could present a risk.

Several factors limit the ability to perform research and interpret results: Regulations may deter investigators and participants. The federal government classifies marijuana as Schedule I, which includes drugs that have no current acceptable medical use and a high potential for abuse. The Michael J. Fox Foundation supported legislation that eliminated barriers to conducting medical cannabis research.

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Studies often have limitations. Size, design, and lack of standardized formulations or dosing make it difficult to compare studies and draw conclusions - 24 Hour Mobile Hydraulic hose repair Newcastle. Many studies include small numbers of participants, so it’s unlikely the group represents the broad Parkinson’s population or that results apply to the majority. Few studies include a placebo group, which makes it difficult to determine how much benefit may truly be from cannabis and how much might be placebo effect.

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There also is a lack of standardization. Different studies use different formulations with different amounts of THC and CBD. Emergency 24 hour Hydraulic hose repair near me Newcastle. This makes it challenging to understand what might be doing what (why one trial fails and another shows positive results, for example) as well as what type of cannabis may work best for an individual or specific symptom.

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They may be able to help you weigh the pros and cons, and they’ll have a complete picture of all your treatments (prescription or otherwise) in case there is a change in symptoms or possible drug interaction. They also can direct you to ongoing research studies, if of interest. If you are thinking about cannabis, you may want to ask your doctor: What symptoms it may help, Be clear about what symptoms you hope to treat — anxiety, sleep, pain or others.

Might cannabis lower blood pressure and counteract the medication you take to raise blood pressure? Or could it worsen your symptoms, such as thinking changes or imbalance? Their recommendation, Some physicians are willing to incorporate cannabis into your treatment regimen; others are less comfortable. Be aware that, unfortunately, many doctors may not know details about the many available products or be able to recommend a specific product or dosing - On-site Hydraulic hose Newcastle.